GIP/GLP-1 peptide reference
Tirzepatide: Reconstitution Math & Reference
By Baris Bingor · Last updated
How do you reconstitute tirzepatide?
Tirzepatide reconstitution is the same arithmetic as any lyophilized peptide: divide vial mass (mg) by added bacteriostatic water (ml) to get mg/ml. A 10 mg vial in 2 ml BAC water gives 5 mg/ml — a 2.5 mg target draw is 0.5 ml, or 50 units on a U-100 syringe. The calculator below does it for any numbers you type.
Reconstitution calculator
Type your own numbers. They aren't sent anywhere: the math runs in your browser.
Type an amount to see the volume and the units.
Arithmetic only. Peptly does not suggest amounts: the amount is yours, from your protocol or the product's documentation. Not medical advice.
What is Tirzepatide?
Tirzepatide is a dual GIP/GLP-1 receptor agonist — a 39-amino-acid synthetic peptide. It is the active ingredient in Mounjaro and Zepbound.
Tirzepatide is FDA-approved as a prescription medication under brand names including Mounjaro (type-2 diabetes) and Zepbound (chronic weight management). It is the active ingredient in those branded auto-injector pens.
Compounded or research-grade tirzepatide commonly ships as lyophilized powder in vials of 5 mg, 10 mg, 15 mg, 20 mg, or 30 mg. Reconstitution math follows the same vial-mass-over-water-volume formula as every other peptide.
Tirzepatide titration is typically slower than semaglutide (longer step intervals at each dose tier). In the Peptly app, each entry keeps the amount exactly as you typed it, so every step is on the record; Peptly never suggests one.
Reconstitution math — reference table
| Vial | BAC water | Concentration | Example dose | U-100 units |
|---|---|---|---|---|
| 5 mg | 1 ml | 5 mg/ml | 2.5 mg | 50 units |
| 10 mg | 1 ml | 10 mg/ml | 2.5 mg | 25 units |
| 10 mg | 2 ml | 5 mg/ml | 5 mg | 100 units |
| 15 mg | 2 ml | 7.5 mg/ml | 7.5 mg | 100 units |
| 20 mg | 2 ml | 10 mg/ml | 10 mg | 100 units |
Storage and shelf-life
Reconstituted tirzepatide is most commonly refrigerated at 2–8 °C and used within 4–6 weeks per common research protocols. Lyophilized powder typically stores at −20 °C until reconstitution.
Tirzepatide in the Peptly app
- A plain-language profile in the library — no amounts, frequencies or regimens.
- Entries exactly as you type them — the app never calculates, converts or suggests an amount.
- Today and reminders — log or skip each entry in one tap, on the schedule you set.
- Injection-site rotation — Peptly suggests the site you used longest ago, other than the last one.
- Private by design — no account; your log stays on your phone.
Other peptide references
- BPC-157 reconstitution math — BPC-157 is a synthetic pentadecapeptide — a 15-amino-acid fragment derived from a protective protein originally isolated from human gastric juice.
- TB-500 reconstitution math — TB-500 is a 17-amino-acid synthetic peptide fragment of Thymosin Beta-4, a regulatory peptide naturally present in most mammalian cells.
- Semaglutide reconstitution math — Semaglutide is a 31-amino-acid GLP-1 receptor agonist.
- Ipamorelin reconstitution math — Ipamorelin is a 5-amino-acid synthetic peptide and a selective growth hormone secretagogue.
- CJC-1295 reconstitution math — CJC-1295 is a synthetic 30-amino-acid analog of growth hormone-releasing hormone (GHRH 1-29), modified for protease resistance.
- Retatrutide reconstitution math — Retatrutide (LY3437943) is an investigational triple-hormone-receptor agonist — it targets the GLP-1, GIP, AND glucagon receptors.
- Tesamorelin reconstitution math — Tesamorelin is a synthetic 44-amino-acid analog of human growth hormone-releasing hormone (GHRH 1-44), stabilized with a trans-3-hexenoic acid group.
- GHK-Cu reconstitution math — GHK-Cu is a copper complex of the naturally occurring tripeptide glycyl-L-histidyl-L-lysine (Gly-His-Lys), which binds a single copper(II) ion.
Related tools and guides
- Main peptide calculator overview
- Peptide reconstitution math reference
- BAC water calculator
- Step-by-step reconstitution guide
- Peptide storage & refrigeration guide
- Peptide dosage unit reference
- Peptide tracker — injection log
Frequently asked questions
How is tirzepatide reconstitution different from semaglutide? +
The math is identical — both are vial mass divided by BAC water. The practical difference is that tirzepatide dose tiers (commonly 2.5 mg → 5 mg → 7.5 mg → 10 mg → 12.5 mg → 15 mg) are larger than semaglutide tiers, so unit counts are typically in the 25-100 range on a U-100 syringe.
What BAC water volume works for a 10 mg tirzepatide vial? +
Common starting points are 1 ml (giving 10 mg/ml, so a 2.5 mg draw = 25 units) or 2 ml (giving 5 mg/ml, so a 2.5 mg draw = 50 units). The calculator on this page shows the unit count for any combination as you type.
Can Peptly remind me when my next tirzepatide entry is due? +
Yes. Set a weekly schedule and Peptly reminds you when each entry is due; one reminder is free, and Peptly Pro adds unlimited reminders with Log and Skip in the notification. Peptly never suggests an amount or a step: when yours changes, you type the new one.
Does the calculator's syringe show partial units? +
The calculator on this page shows the units to one decimal and draws the fill on a U-100 syringe: for a draw like 12.5 units, the fill stops halfway between 12 and 13.
Is tirzepatide approved for human use? +
Yes — tirzepatide is FDA-approved under brand names including Mounjaro and Zepbound. Compounded or research-grade vials are a different supply category. This page is a math reference and the Peptly app is a log — neither is a prescription substitute.